Applications
Discover the various applications in which the DECRO solution can be used.
Real-time, non-invasive physiological monitoring is a major challenge in biomedical research, veterinary medicine, and scientific training.
By being completely non-invasive, ETISENSE’s telemetry solution provides real-time access to high-quality ECG, as well as ventilation/pulmonary/respiratory and activity measurements, without the need for implantable surgery (DECRO). It allows monitoring of precise and continuous data, over 24-hour periods or during longitudinal measurements lasting a few hours, thereby promoting advancements in several key areas.
DECRO Solution Through Applications
Phenotyping of disease models
Monitoring of ECG morphological changes, ventilation, and locomotor activity patterns changes to better characterize pathological phenotypes and understand underlying pathophysiological mechanisms.
Pharmacology and safety-toxicology
Assessment of the efficacy and toxicity of novel pharmacological compounds on cardiorespiratory and central nervous system (CNS) functions in rodent and non-rodent species using jacketed telemetry.
Monitoring of vital functions
Monitor the health status of your animals following a medical condition or surgery (e.g., cardiac stroke), or anticipate humane endpoints in severe procedures using jacketed telemetry — all while allowing a return to the home cage.
Education and training
Learn physiology and pharmacology using jacketed telemetry on rehomed animals, or through a new digital approach with pre-recorded, on-demand datasets from cardiorespiratory studies.
Veterinary
Use wearable telemetry to monitor vital signs (heart and respiratory rates) or the development of medical conditions (e.g., cardiopathy), either at home or at the veterinary clinic.
Key Publications on DECRO Use Cases
Altered ECG parameters with loss of cardiac variability and prolonged QTc in a non-diabetic chronic kidney disease rat model
Matthieu Soulié1, Leandro Fontana Pires2, Agathe Cambier2, Ixchel Lima-Posada1, Frédéric Jaisser1 ¹ Inserm, UMRS 1138, centre de recherche des cordeliers, campus des cordeliers - Sorbonne université, Paris, France² Physiological monitoring instruments, ETISENSE SAS,...
Hemodynamic monitoring with thoracocardiography: Validation by beta-adrenergic modulation in anesthetized rats
Leandro Fontana Pires1,2, Agathe Cambier2, Stéphane Tanguy1, Charles Eynard2, Timothé Flenet2, Pierre-Yves Gumery1, François Boucher1 ¹ PRETA TEAM, TIMC IMAG, 38706 La Tronche CEDEX, France;² R&D, ETISENSE SAS, 69008 LYON, France...
A unifying method to study respiratory sinus arrhythmia dynamics implemented in a new toolbox
Valentin Ghibaudo,¹ Jules Granget,¹,³ Matthias Dereli,¹ Nathalie Buonviso,¹,² and Samuel Garcia¹,² ¹Centre de Recherche en Neuroscience de Lyon, Lyon, 69500, France²Centre National de la Recherche Scientifique, Lyon, 69500, France³Institut National de la Santé et de...
Marmoset (a small size NHP): Incorporation of safety pharmacology endpoints in toxicology studies
Marmoset (a small size NHP): Incorporation of safety pharmacology endpoints in toxicology studiesRaafat Fares and Pascal Champéroux European Research Biology Center (ERBC), Baugy, France Safety Pharmacology Society Annual Meeting, 2023 Abstract The common marmoset...