Applications
Discover the various applications in which the DECRO solution can be used.
Real-time, non-invasive physiological monitoring is a major challenge in biomedical research, veterinary medicine, and scientific training.
By being completely non-invasive, ETISENSE’s telemetry solution provides real-time access to high-quality ECG, as well as ventilation/pulmonary/respiratory and activity measurements, without the need for implantable surgery (DECRO). It allows monitoring of precise and continuous data, over 24-hour periods or during longitudinal measurements lasting a few hours, thereby promoting advancements in several key areas.
DECRO Solution Through Applications
Phenotyping of disease models
Monitoring of ECG morphological changes, ventilation, and locomotor activity patterns changes to better characterize pathological phenotypes and understand underlying pathophysiological mechanisms.
Pharmacology and safety-toxicology
Assessment of the efficacy and toxicity of novel pharmacological compounds on cardiorespiratory and central nervous system (CNS) functions in rodent and non-rodent species using jacketed telemetry.
Monitoring of vital functions
Monitor the health status of your animals following a medical condition or surgery (e.g., cardiac stroke), or anticipate humane endpoints in severe procedures using jacketed telemetry — all while allowing a return to the home cage.
Education and training
Learn physiology and pharmacology using jacketed telemetry on rehomed animals, or through a new digital approach with pre-recorded, on-demand datasets from cardiorespiratory studies.
Veterinary
Use wearable telemetry to monitor vital signs (heart and respiratory rates) or the development of medical conditions (e.g., cardiopathy), either at home or at the veterinary clinic.
Key Publications on DECRO Use Cases
Non-Invasive Monitoring Of Cardiac Output: Validation In Anesthetized Laboratory Rats By Pharmacological Beta-Adrenergic Pathway Modulation
Non-Invasive Monitoring Of Cardiac Output: Validation In Anesthetized Laboratory Rats By Pharmacological Beta-Adrenergic Pathway ModulationLeandro Fontana Pires1,2, Agathe Cambier2, Stéphane Tanguy1, Charles Eynard2, Timothé Flenet2, Pierre-Yves Gumery1, François...
Intérêt de la surveillance cardiorespiratoire non invasive chez le rat pour le raffinement de protocoles chirurgicaux
Intérêt de la surveillance cardiorespiratoire non invasive chez le rat pour le raffinement de protocoles chirurgicauxCambier A.1,2, Tanguy S.1, Flenet T.2, Boucher F.1 ¹ PRETA TIMC-IMAG, Université Grenoble Alpes, La Tronche² ETISENSE, Lyon, France 47th AFSTAL...
Evaluation of jacketed telemetry in rats for cardiorespiratory phenotyping at exercise
Evaluation of jacketed telemetry in rats for cardiorespiratory phenotyping at exerciseT. Flenet1 ; S. Tanguy2 ; A. Cambier1,2 ; E. Charles1 ; F. Boucher2 ¹ Biomedical engineering, ETISENSE SAS, Lyon, France; ² CNRS, timc-imag umr 5525, Université Grenoble Alpes,...
Simultaneous assessment of central nervous and respiratory systems using jacketed telemetry in socially-housed rats: Application of the “3Rs” principles in core battery safety pharmacology studies
Simultaneous assessment of central nervous and respiratory systems using jacketed telemetry in socially-housed rats: Application of the “3Rs” principles in core battery safety pharmacology studiesR. Fares & P. Champeroux, ERBC FOB test and respiratory study in the...