Applications
Discover the various applications in which the DECRO solution can be used.
Real-time, non-invasive physiological monitoring is a major challenge in biomedical research, veterinary medicine, and scientific training.
By being completely non-invasive, ETISENSE’s telemetry solution provides real-time access to high-quality ECG, as well as ventilation/pulmonary/respiratory and activity measurements, without the need for implantable surgery (DECRO). It allows monitoring of precise and continuous data, over 24-hour periods or during longitudinal measurements lasting a few hours, thereby promoting advancements in several key areas.
DECRO Solution Through Applications
Phenotyping of disease models
Monitoring of ECG morphological changes, ventilation, and locomotor activity patterns changes to better characterize pathological phenotypes and understand underlying pathophysiological mechanisms.
Pharmacology and safety-toxicology
Assessment of the efficacy and toxicity of novel pharmacological compounds on cardiorespiratory and central nervous system (CNS) functions in rodent and non-rodent species using jacketed telemetry.
Monitoring of vital functions
Monitor the health status of your animals following a medical condition or surgery (e.g., cardiac stroke), or anticipate humane endpoints in severe procedures using jacketed telemetry — all while allowing a return to the home cage.
Education and training
Learn physiology and pharmacology using jacketed telemetry on rehomed animals, or through a new digital approach with pre-recorded, on-demand datasets from cardiorespiratory studies.
Veterinary
Use wearable telemetry to monitor vital signs (heart and respiratory rates) or the development of medical conditions (e.g., cardiopathy), either at home or at the veterinary clinic.
Key Publications on DECRO Use Cases
Feasibility of Non-Invasive Monitoring of Respiratory, ECG and Activity Parameters in Pair-Housed Freely-Moving Adult Male Rats Using a Jacketed External Telemetry System (DECRO®); A Pharmacological Validation with Baclofen
S Baudet¹, R Fares², J Vial¹, M Ravaz¹, V Roger¹, C Bory¹, T Flénet² ¹ Charles River Laboratories France Safety Assessment SAS, Lyon, France² Etisense SAS, Lyon, France Safety Pharmacology Society Annual Meeting, Virtual, 2021, 06/10 Abstract Simultaneous assessment...
Implementation of cardiorespiratory monitoring in the juvenile minipig using a non-invasive jacketed telemetry system
PENARD L², FLENET T¹, EYNARD C¹, BOUILLON C¹, BORY C², BAUDET S², MARSDEN E². ¹ ETISENSE SAS, Lyon, France² Charles River Laboratories France Safety Assessment SAS, Lyon, France. Society for Birth Defects Research & Prevention 61st Annual Meeting June 24–July 1,...
Assessment of the Feasibility of Cardiorespiratory Monitoring in the Juvenile Minipig Using a Noninvasive Jacketed Telemetry System
SIMON C¹, EYNARD C¹, FLENET T¹, PENARD L², BORY C², BAUDET S², MARSDEN E². ¹ ETISENSE, Lyon, Rhône-Alpes, France² Charles River Laboratories France Safety Assessment SAS, Saint-Germain-Nuelles, Rhône-Alpes, France. Society for Birth Defects Research & Prevention...
Simultaneous non-invasive telemetric electrocardiogram and respiratory measurement with a connected jacket in rats
Raafat P. FARES¹, Alexia BOIRE², Charles EYNARD¹, Timothé FLENET¹ ¹ ETISENSE SAS, R&D department, 60A avenue Rockefeller, 69008 LYON France ² Université de Lyon, Univ. Claude Bernard Lyon 1, Master in Integrative Biology and Physiology, 43 Bd du 11 Novembre 1918,...