Applications
Discover how DECRO is applied across different study types and research environments.
Real-time, non-invasive physiological monitoring is a major challenge in biomedical research, veterinary medicine, and scientific training.
By being completely non-invasive, ETISENSE’s telemetry solution provides real-time access to high-quality ECG, as well as ventilation/pulmonary/respiratory and activity measurements, without the need for implantable surgery. It allows monitoring of precise and continuous data, over 24-hour periods or during longitudinal measurements lasting a few hours, thereby promoting advancements in several key areas.
DECRO Solution Through Applications
Phenotyping of disease models
Monitoring of ECG morphological changes, ventilation, and locomotor activity patterns changes to better characterize pathological phenotypes and understand underlying pathophysiological mechanisms.
Pharmacology and safety-toxicology
Assessment of the efficacy and toxicity of novel pharmacological compounds on cardiorespiratory and central nervous system (CNS) functions in rodent and non-rodent species using jacketed telemetry.
Monitoring of vital functions
Monitor the health status of your animals following a medical condition or surgery (e.g., cardiac stroke), or anticipate humane endpoints in severe procedures using jacketed telemetry — all while allowing a return to the home cage.
Education and training
Learn physiology and pharmacology using jacketed telemetry on rehomed animals, or through a new digital approach with pre-recorded, on-demand datasets from cardiorespiratory studies.
Veterinary
Use wearable telemetry to monitor vital signs (heart and respiratory rates) or the development of medical conditions (e.g., cardiopathy), either at home or at the veterinary clinic.
Key Publications on DECRO Use Cases
A new non-invasive cardiorespiratory telemetry jacket for rodents
Timothé Flenet1, H. Barret2, E. Chastel2, A. Momtaz2, C. Eynard1 and C. Boixel2 1 R&D, ETISENSE SAS, Lyon, France2 Preclinical Safety, SANOFI, Alfortville, France Laboratory Animals 2019, Vol. 53 [1S] 28-203, abstracts of 14th FELASA annual congress...
Inductive plethysmography in rats: towards a new standard for longitudinal non-invasive cardiac output monitoring in preclinical studies
J Fontecave-Jallon¹, T Flénet¹, C Eynard¹, P-Y Guméry¹, F Boucher¹ and S Tanguy¹ ¹ PRETA Team, Université Grenoble Alpes, CNRS, CHU Grenoble Alpes, Grenoble INP, TIMC-IMAG, F-38000 Grenoble, France Physiological Measurement, Volume 39, Number 9, 2018...
High-resolution respiratory inductive plethysmography in rats: validation in anesthetized conditions
Respiratory monitoring is often required in experimental physiological and pharmacological studies in rodents. Currently, the mostly used techniques are direct measurement of airflow on intubated animals and whole body plethysmography. Objective: Although the...
High-resolution respiratory inductive plethysmography in rats: validation in anesthetized conditions
T Flénet¹, J Fontecave-Jallon¹, P-Y Guméry¹, C Eynard¹, F Boucher¹, P Baconnier¹ and S Tanguy¹ ¹ Université Grenoble Alpes, CNRS, TIMC-IMAG Laboratory UMR 5525, PRETA team, F-38041 Grenoble, France Physiological Measurement, Volume 38, Number 7,...