Applications
Discover the various applications in which the DECRO solution can be used.
Real-time, non-invasive physiological monitoring is a major challenge in biomedical research, veterinary medicine, and scientific training.
By being completely non-invasive, ETISENSE’s telemetry solution provides real-time access to high-quality ECG, as well as ventilation/pulmonary/respiratory and activity measurements, without the need for implantable surgery (DECRO). It allows monitoring of precise and continuous data, over 24-hour periods or during longitudinal measurements lasting a few hours, thereby promoting advancements in several key areas.
DECRO Solution Through Applications
Phenotyping of disease models
Monitoring of ECG morphological changes, ventilation, and locomotor activity patterns changes to better characterize pathological phenotypes and understand underlying pathophysiological mechanisms.
Pharmacology and safety-toxicology
Assessment of the efficacy and toxicity of novel pharmacological compounds on cardiorespiratory and central nervous system (CNS) functions in rodent and non-rodent species using jacketed telemetry.
Monitoring of vital functions
Monitor the health status of your animals following a medical condition or surgery (e.g., cardiac stroke), or anticipate humane endpoints in severe procedures using jacketed telemetry — all while allowing a return to the home cage.
Education and training
Learn physiology and pharmacology using jacketed telemetry on rehomed animals, or through a new digital approach with pre-recorded, on-demand datasets from cardiorespiratory studies.
Veterinary
Use wearable telemetry to monitor vital signs (heart and respiratory rates) or the development of medical conditions (e.g., cardiopathy), either at home or at the veterinary clinic.
Key Publications on DECRO Use Cases
Jacketed Telemetry with Integrated ECG electrodes: A Comparison with Traditional Implants in Beagle Dogs
FARES Raafat1, BENDRIMIA Anes1, BOUARD Delphine1, CAMBIER Agathe2, NADJAR Clémence2, EYNARD Charles2, FLENET Timothé2, Pascal CHAMPEROUX1 1ERBC Chemin de Montifault, 18800 Baugy, France2R&D Department, ETISENSE, Lyon, RHONE, FranceAbstract Jacket telemetry...
Eplerenone treatment limit electrocardiogram alteration in a non-diabetic chronic kidney disease rat model
Matthieu Soulié1, Tania Sanchez-Bayuela1, Agathe Cambier2, Frédéric Jaisser1 ¹ Inserm, UMRS 1166, Paris, France² Physiological monitoring instruments, ETISENSE SAS, Lyon, France https://doi.org/10.1161/hyp.82.suppl_1.079Abstract Background: Chronic Kidney Disease...
Jacketed telemetry in rats: a novel non-invasive method for cardiorespiratory phenotyping during treadmill exercise
Stephane Tanguy1, Agathe Cambier2, Leandro Fontana-Pires1,2, Timothe Flenet2, Charles Eynard2, Julie Fontecave-Jalon1, Pierre-Yves Gumery1 and François Boucher1 1 Universite Grenoble Alpes, CNRS, UMR 5525, VetAgro Sup, Grenoble INP, T IMC, 38000 Grenoble, France2...
Evaluating a non-invasive telemetry jacket as an alternative to the reference methods for cardio-respiratory safety pharmacological testing in rats
Khamlichi Fatima-Zahra1, Schauerte Heike1, Mayer Werner1 , Hezler Leonie-Theresa2, Martel Eric1 , Rast Georg1 , Pairet Nicolas 1 1 Boehringer Ingelheim Pharma, Department of Drug Discovery Sciences-General Pharmacology, Biberach/Riss, Germany2 Boehringer Ingelheim...